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prf1 prf1 tuf tuf APE_1119.1 APE_1119.1 rpl15e rpl15e rps3ae rps3ae aif2a aif2a aif2b aif2b aif2g aif2g rplP0 rplP0 APE_0554.1 APE_0554.1 rpl24p rpl24p
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
prf1Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Belongs to the eukaryotic release factor 1 family. (373 aa)    
Predicted Functional Partners:
tuf
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 0.997
APE_1119.1
ABCE1 homolog.
  
 
 0.990
rpl15e
50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.887
rps3ae
30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.886
aif2a
Translation initiation factor 2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
  
 
 0.872
aif2b
Translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
  
  
 0.867
aif2g
Translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
  
 0.860
rplP0
50S ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.855
APE_0554.1
Putative methyltransferase.
   
 0.849
rpl24p
50S ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
  0.823
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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