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argG-2 argG-2 argH-2 argH-2 BPSL1715 BPSL1715 argH argH BPSL2214 BPSL2214 carB carB argF argF argA argA arcB arcB BPSL2101 BPSL2101 purA purA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Experiments
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[Homology]
Score
argG-2Similar to Streptomyces clavuligerus argininosuccinate synthase ArgG SWALL:ASSY_STRCL (SWALL:P50986) (397 aa) fasta scores: E(): 8.4e-49, 35.78% id in 394 aa, and to Thermoanaerobacter tengcongensis argininosuccinate synthase tte2494 SWALL:Q8R7C2 (EMBL:AE013190) (410 aa) fasta scores: E(): 1.9e-70, 44.92% id in 394 aa. (404 aa)    
Predicted Functional Partners:
argH-2
Similar to Escherichia coli argininosuccinate lyase ArgH or b3960 SWALL:ARLY_ECOLI (SWALL:P11447) (457 aa) fasta scores: E(): 7.9e-63, 43.26% id in 453 aa, and to Bacillus subtilis argininosuccinate lyase ArgH SWALL:ARLY_BACSU (SWALL:O34858) (461 aa) fasta scores: E(): 1.8e-70, 44.13% id in 460 aa.
 
 
 0.997
BPSL1715
Putative bifunctional protein (ligase and argininosuccinate lyase); Similar to full length of Rhizobium loti fusion protein contains putative ligase and probable arginosuccinate lyase msi203 SWALL:CAD31608 (EMBL:AL672113) (899 aa) fasta scores: E(): 5.4e-96, 38.52% id in 911 aa, and C-terminal region similar to Escherichia coli argininosuccinate lyase ArgH or b3960 SWALL:ARLY_ECOLI (SWALL:P11447) (457 aa) fasta scores: E(): 1.2e-25, 32.44% id in 376 aa.
 
 
 0.995
argH
Similar to Escherichia coli argininosuccinate lyase ArgH or b3960 SWALL:ARLY_ECOLI (SWALL:P11447) (457 aa) fasta scores: E(): 9.8e-72, 44.97% id in 458 aa, to Pseudomonas aeruginosa argininosuccinate lyase ArgH or pa5263 SWALL:ARLY_PSEAE (SWALL:P50987) (464 aa) fasta scores: E(): 1.5e-110, 64.51% id in 465 aa, and to Ralstonia solanacearum argininosuccinate lyase rsc2363 or rs01183 SWALL:ARLY_RALSO (SWALL:Q8XWV7) (471 aa) fasta scores: E(): 1.5e-143, 82.09% id in 469 aa.
 
 
 0.991
BPSL2214
Similar to Rhizobium loti fusion protein contains putative ligase and probable arginosuccinate lyase msi203 SWALL:CAD31608 (EMBL:AL672113) (899 aa) fasta scores: E(): 7.9e-99, 38.19% id in 906 aa, N-terminal region to Rhizobium loti putative ligase/carboxylase protein msi201 SWALL:CAD31606 (EMBL:AL672113) (425 aa) fasta scores: E(): 5.4e-25, 31.08% id in 415 aa and C-terminal region to Rhizobium loti argininosuccinate lyase mll9226 SWALL:Q981V0 (EMBL:AP003015) (927 aa) fasta scores: E(): 4.4e-94, 37.19% id in 898 aa.
 
 
 0.991
carB
Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 68.93% id in 1088 aa, and to Ralstonia solanacearum carbamoyl-phosphate synthase large chain rsc1521 or rs03783 SWALL:Q8XZ83 (EMBL:AL646065) (1081 aa) fasta scores: E(): 0, 85.82% id in 1086 aa; Belongs to the CarB family.
 
 0.987
argF
Putative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.975
argA
Putative amino-acid acetyltransferase; Similar to Escherichia coli, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.5e-76, 46.89% id in 435 aa, and to Ralstonia solanacearum probable amino-acid acetyltransferase protein rsc1250 or rs02762 SWALL:Q8XZZ5 (EMBL:AL646063) (451 aa) fasta scores: E(): 3.6e-123, 71.71% id in 449 aa. CDS is extended at the N-terminus in comparison to some orthologues. Possible alternative translational start site.
 
  
 0.975
arcB
Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.970
BPSL2101
Subfamily M20A unassigned peptidase; Similar to Escherichia coli acetylornithine deacetylase ArgE or b3957 SWALL:ARGE_ECOLI (SWALL:P23908) (383 aa) fasta scores: E(): 7.7e-24, 32.87% id in 365 aa, and to Ralstonia solanacearum probable acetylornithine deacetylase rsc1641 or rs04016 SWALL:Q8XYW5 (EMBL:AL646065) (397 aa) fasta scores: E(): 3.3e-107, 67.18% id in 384 aa.
  
 0.969
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.927
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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