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mdh mdh BPSS0372 BPSS0372 gltA gltA BPSL0890 BPSL0890 fumC fumC maeB maeB BPSL3242 BPSL3242 icd icd aceB aceB pckG pckG ppc ppc
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query proteins and first shell of interactors
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)    
Predicted Functional Partners:
BPSS0372
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.997
gltA
Citrate synthase; Similar to Rhizobium meliloti citrate synthase GltA or r01509 or smc02087 SWALL:CISY_RHIME (SWALL:O33915) (429 aa) fasta scores: E(): 1.4e-128, 70.23% id in 430 aa, and to Ralstonia solanacearum probable citrate synthase protein rsc1991 or rs03559 SWALL:Q8XXX2 (EMBL:AL646067) (433 aa) fasta scores: E(): 6.9e-149, 82.44% id in 433 aa.
  
 0.983
BPSL0890
Putative citrate synthase; C-terminal region is similar to Agrobacterium tumefaciens citrate synthase CisZ or atu4851 or agr_l_71 SWALL:Q8U6F6 (EMBL:AE009414) (335 aa) fasta scores: E(): 6.7e-14, 42.68% id in 335 aa, and to Staphylococcus aureus citrate synthase II CitZ SWALL:Q99TG7 (EMBL:AP003363) (373 aa) fasta scores: E(): 4.7e-13, 27.36% id in 391 aa. Possible alternative translational start site.
  
 0.981
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.975
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 5.4e-181, 61.8% id in 754 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein rsc2767 or rs00080 SWALL:Q8XVR2 (EMBL:AL646071) (781 aa) fasta scores: E(): 0, 78.28% id in 760 aa.
  
 0.967
BPSL3242
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 1.6e-184, 63.72% id in 758 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein MaeB1 or Rsc2123 or Rs03232 SWALL:Q8XXJ0 (EMBL:AL646068) (773 aa) fasta scores: E(): 5.7e-194, 67.86% id in 753 aa; Belongs to the malic enzymes family.
  
 0.967
icd
Similar to Alcaligenes eutrophus isocitrate dehydrogenase isozyme 1 Icd1 SWALL:CAD32550 (EMBL:AJ488288) (442 aa) fasta scores: E(): 5.7e-133, 85.81% id in 416 aa, and to Ralstonia solanacearum probable isocitrate dehydrogenase Icd or rsc2490 or rs01106 SWALL:Q8XWI4 (EMBL:AL646070) (416 aa) fasta scores: E(): 2.5e-139, 88.7% id in 416 aa.
  
 
 0.958
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 1.9e-103, 50.84% id in 533 aa, and to Ralstonia solanacearum probable malate synthase A rsc1363 or rs04645 SWALL:Q8XZN2 (EMBL:AL646064) (529 aa) fasta scores: E(): 1.5e-177, 79.84% id in 531 aa.
   
 0.950
pckG
Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
 
  
 0.946
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.930
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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