STRINGSTRING
PM0747 PM0747 surE surE PM1193 PM1193 PM1545 PM1545 tmk tmk thyA thyA cdd cdd cmkA cmkA dut dut tdk tdk deoD deoD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PM0747Unknown; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (195 aa)    
Predicted Functional Partners:
surE
SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.913
PM1193
Unknown; Belongs to the 5'-nucleotidase family.
     
 0.905
PM1545
Unknown.
     
 0.904
tmk
Unknown; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
  0.901
thyA
ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
  0.900
cdd
Cdd; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
     
  0.900
cmkA
CmkA.
     
  0.900
dut
Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
  0.900
tdk
Tdk.
    
  0.900
deoD
DeoD.
     
 0.900
Your Current Organism:
Pasteurella multocida Pm70
NCBI taxonomy Id: 272843
Other names: P. multocida subsp. multocida str. Pm70, Pasteurella multocida subsp. multocida Pm70, Pasteurella multocida subsp. multocida str. Pm70, Pasteurella multocida subsp. multocida strain Pm70
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.