node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_0119 | mraY | RSP_0119 | RSP_2101 | PA-phosphatase related phosphoesterase; IMG reference gene:2512955110; PFAM: PAP2 superfamily. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.911 |
RSP_0119 | uppP | RSP_0119 | RSP_1150 | PA-phosphatase related phosphoesterase; IMG reference gene:2512955110; PFAM: PAP2 superfamily. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.923 |
ddlA | ftsI | RSP_2111 | RSP_2098 | D-alanine--D-alanine ligase; Cell wall formation. | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | 0.882 |
ddlA | ftsW | RSP_2111 | RSP_2106 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsW; IMG reference gene:2512954030; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | 0.991 |
ddlA | mraY | RSP_2111 | RSP_2101 | D-alanine--D-alanine ligase; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.972 |
ddlA | murC | RSP_2111 | RSP_2108 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
ddlA | murD | RSP_2111 | RSP_2103 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.989 |
ddlA | murE | RSP_2111 | RSP_2099 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.959 |
ddlA | murF | RSP_2111 | RSP_2100 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddlA | murG | RSP_2111 | RSP_2107 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.997 |
ftsI | ddlA | RSP_2098 | RSP_2111 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | D-alanine--D-alanine ligase; Cell wall formation. | 0.882 |
ftsI | ftsW | RSP_2098 | RSP_2106 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Cell division protein FtsW; IMG reference gene:2512954030; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | 0.988 |
ftsI | mraY | RSP_2098 | RSP_2101 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.944 |
ftsI | murC | RSP_2098 | RSP_2108 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.877 |
ftsI | murD | RSP_2098 | RSP_2103 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.926 |
ftsI | murE | RSP_2098 | RSP_2099 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.997 |
ftsI | murF | RSP_2098 | RSP_2100 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.963 |
ftsI | murG | RSP_2098 | RSP_2107 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.851 |
ftsW | ddlA | RSP_2106 | RSP_2111 | Cell division protein FtsW; IMG reference gene:2512954030; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.991 |
ftsW | ftsI | RSP_2106 | RSP_2098 | Cell division protein FtsW; IMG reference gene:2512954030; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family. | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | 0.988 |