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pyrG pyrG guaA-2 guaA-2 rps2AB rps2AB ndk ndk rpl13AB rpl13AB rpl1AB rpl1AB argS argS dcD-1 dcD-1 rpl6AB rpl6AB rplp0 rplp0 infB infB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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pyrGCTP synthetase (UTP-ammonia lyase) (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (By similarity). (535 aa)    
Predicted Functional Partners:
guaA-2
GMP synthase, PP-ATPase domain (guaA); Catalyzes the synthesis of GMP from XMP.
  
 
 0.967
rps2AB
SSU ribosomal protein S2AB (rps2AB); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.962
ndk
Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.959
rpl13AB
LSU ribosomal protein L13AB (rpl13AB); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.955
rpl1AB
LSU ribosomal protein L1AB (rpl1AB); Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA (Probable).
  
 
 0.937
argS
Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.931
dcD-1
Deoxycytidine triphosphate deaminase (dcD-1); Catalyzes the deamination of dCTP to dUTP.
  
 
 0.928
rpl6AB
LSU ribosomal protein L6AB (rpl6AB); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
 
 0.922
rplp0
LSU acidic ribosomal protein P0 homolog (rplp0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
   
 
 0.920
infB
Translation initiation factor IF2 homolog (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
 
 0.918
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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