STRINGSTRING
AarF AarF RecJ RecJ TTE1841 TTE1841 SecF SecF SecD SecD PaaY2 PaaY2 AslB3 AslB3 FusA FusA RplB RplB HisI HisI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AarFPredicted unusual protein kinase; Best Blastp hit = gi|10175329|dbj|BAB06427.1| (AP001516) ABC transporter [Bacillus halodurans], score 318, E-value 1.00E-85. (555 aa)    
Predicted Functional Partners:
RecJ
Best Blastp hit = gi|7475820|pir||H69980 single-strand DNA-specific exonuclease homolog yrvE - Bacillus subtilis gi|2635226|emb|CAB14721.1| (Z99118) similar to single-strand DNA-specific exonuclease [Bacillus subtilis], score 390, E-value 1.00E-107.
      0.810
TTE1841
Conserved hypothetical protein; Best Blastp hit = gi|10175330|dbj|BAB06428.1| (AP001516) BH2709; unknown [Bacillus halodurans], score 70.5, E-value 5.00E-12.
 
     0.649
SecF
Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.612
SecD
Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.603
PaaY2
Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; Best Blastp hit = gi|2493491|sp|Q57752|Y304_METJA HYPOTHETICAL PROTEIN MJ0304 gi|2127899|pir||A64338 ferripyochelin binding protein homolog - Methanococcus jannaschii gi|1591027|gb|AAB98291.1| (U67485) ferripyochelin binding protein (fbp) [Methanococcus jannaschii], score 169, E-value 2.00E-41.
       0.565
AslB3
Arylsulfatase regulator (Fe-S oxidoreductase); Best Blastp hit = gi|7462068|pir||H72266 astB/chuR-related protein - Thermotoga maritima (strain MSB8) gi|4981883|gb|AAD36396.1|AE001787_1 (AE001787) astB/chuR-related protein [Thermotoga maritima], score 99.8, E-value 7.00E-20.
       0.563
FusA
Translation elongation and release factors (GTPases); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPas [...]
      
 0.489
RplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.439
HisI
Phosphoribosyl-AMP cyclohydrolase; Best Blastp hit = gi|6175609|gb|AAF05095.1|AF150930_4 (AF150930) phosphoribosyl-AMP cyclohydrolase [Thermoanaerobacter ethanolicus], score 237, E-value 8.00E-62; In the C-terminal section; belongs to the PRA-PH family.
       0.403
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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