node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ILVA | ILVD | WS0132 | WS0130 | THREONINE DEHYDRATASE BIOSYNTHETIC. | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 0.990 |
ILVA | ILVH | WS0132 | WS0102 | THREONINE DEHYDRATASE BIOSYNTHETIC. | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 0.978 |
ILVA | ILVI | WS0132 | WS0103 | THREONINE DEHYDRATASE BIOSYNTHETIC. | ACETOLACTATE SYNTHASE LARGE SUBUNIT. | 0.954 |
ILVA | WS2128 | WS0132 | WS2128 | THREONINE DEHYDRATASE BIOSYNTHETIC. | PYRUVATE FERREDOXIN OXIDOREDUCTASE, BETA SUBUNIT. | 0.821 |
ILVA | WS2130 | WS0132 | WS2130 | THREONINE DEHYDRATASE BIOSYNTHETIC. | PYRUVATE SYNTHASE SUBUNIT PORA PYRUVATE OXIDOREDUCTASEALPHA CHAIN POR PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT. | 0.821 |
ILVA | ilvC | WS0132 | WS1878 | THREONINE DEHYDRATASE BIOSYNTHETIC. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.724 |
ILVA | leuB | WS0132 | WS1813 | THREONINE DEHYDRATASE BIOSYNTHETIC. | ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.955 |
ILVD | ILVA | WS0130 | WS0132 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | THREONINE DEHYDRATASE BIOSYNTHETIC. | 0.990 |
ILVD | ILVH | WS0130 | WS0102 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 0.913 |
ILVD | ILVI | WS0130 | WS0103 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | ACETOLACTATE SYNTHASE LARGE SUBUNIT. | 0.988 |
ILVD | LEUA | WS0130 | WS0624 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.976 |
ILVD | ilvC | WS0130 | WS1878 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.995 |
ILVD | leuB | WS0130 | WS1813 | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.909 |
ILVH | ILVA | WS0102 | WS0132 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | THREONINE DEHYDRATASE BIOSYNTHETIC. | 0.978 |
ILVH | ILVD | WS0102 | WS0130 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family. | 0.913 |
ILVH | ILVI | WS0102 | WS0103 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | ACETOLACTATE SYNTHASE LARGE SUBUNIT. | 0.999 |
ILVH | LEUA | WS0102 | WS0624 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | 2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.932 |
ILVH | WS1068 | WS0102 | WS1068 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE. | 0.913 |
ILVH | WS1069 | WS0102 | WS1069 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE. | 0.906 |
ILVH | WS2128 | WS0102 | WS2128 | ACETOLACTATE SYNTHASE SMALL SUBUNIT. | PYRUVATE FERREDOXIN OXIDOREDUCTASE, BETA SUBUNIT. | 0.903 |