node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lxx10150 | aceE | Lxx10150 | Lxx12700 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.979 |
Lxx10150 | gltA2 | Lxx10150 | Lxx16220 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | Citrate synthase; Identified by sequence similarity; Belongs to the citrate synthase family. | 0.503 |
Lxx10150 | pdhA | Lxx10150 | Lxx25070 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | Pyruvate dehydrogenase E1 component, alpha subunit; Identified by sequence similarity. | 0.990 |
Lxx10150 | pdhB-2 | Lxx10150 | Lxx25060 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.996 |
Lxx10150 | pdhC | Lxx10150 | Lxx25050 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | Dihydrolipoamide acyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.994 |
Lxx10150 | sucA | Lxx10150 | Lxx19140 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | 2-oxoglutarate dehydrogenase; Identified by sequence similarity. | 0.999 |
Lxx10150 | sucC | Lxx10150 | Lxx19720 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.411 |
accC | gltA2 | Lxx04730 | Lxx16220 | Biotin carboxylase; Identified by sequence similarity. | Citrate synthase; Identified by sequence similarity; Belongs to the citrate synthase family. | 0.844 |
accC | pdhB-2 | Lxx04730 | Lxx25060 | Biotin carboxylase; Identified by sequence similarity. | Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.489 |
accC | pdhC | Lxx04730 | Lxx25050 | Biotin carboxylase; Identified by sequence similarity. | Dihydrolipoamide acyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.916 |
accC | pta | Lxx04730 | Lxx03410 | Biotin carboxylase; Identified by sequence similarity. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.924 |
accC | sucC | Lxx04730 | Lxx19720 | Biotin carboxylase; Identified by sequence similarity. | succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.833 |
accC | sucD | Lxx04730 | Lxx19700 | Biotin carboxylase; Identified by sequence similarity. | succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.823 |
aceE | Lxx10150 | Lxx12700 | Lxx10150 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase; Identified by sequence similarity. | 0.979 |
aceE | gltA2 | Lxx12700 | Lxx16220 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Citrate synthase; Identified by sequence similarity; Belongs to the citrate synthase family. | 0.473 |
aceE | pdhA | Lxx12700 | Lxx25070 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase E1 component, alpha subunit; Identified by sequence similarity. | 0.942 |
aceE | pdhB-2 | Lxx12700 | Lxx25060 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.922 |
aceE | pdhC | Lxx12700 | Lxx25050 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide acyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.980 |
aceE | pta | Lxx12700 | Lxx03410 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.607 |
aceE | sucA | Lxx12700 | Lxx19140 | Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase; Identified by sequence similarity. | 0.863 |