STRINGSTRING
ar ar MDM2 MDM2 Prkaca Prkaca prkacb prkacb CTNNB1 CTNNB1 KDM1A KDM1A FKBP4 FKBP4 NCOA1 NCOA1 NCOA2 NCOA2 NCOA3 NCOA3 FKBP5 FKBP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arAndrogen receptor. (232 aa)    
Predicted Functional Partners:
MDM2
MDM2 proto-oncogene.
    
 0.940
Prkaca
Uncharacterized protein.
     
 0.907
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.907
CTNNB1
Catenin beta 1.
    
 
 0.895
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.890
FKBP4
Peptidylprolyl isomerase.
    
 0.852
NCOA1
Nuclear receptor coactivator.
    
 0.838
NCOA2
Nuclear receptor coactivator.
    
 0.838
NCOA3
Nuclear receptor coactivator.
    
 0.838
FKBP5
Peptidylprolyl isomerase.
    
 0.826
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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