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fumC fumC sdhA sdhA fumA fumA mdh mdh BBta_3876 BBta_3876 sdhC sdhC sdhB sdhB BBta_5810 BBta_5810 BBta_7568 BBta_7568 glcB glcB sdhD sdhD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (474 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase subunit A; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 6 : Inner membrane-associated; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.994
fumA
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.993
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.978
BBta_3876
Malic oxidoreductase; Phosphotransacetylase (part 2); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
  
 
 0.972
sdhC
Succinate dehydrogenase subunit C; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 6 : Inner membrane-associated.
  
 
 0.970
sdhB
Succinate dehydrogenase subunit B; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 6 : Inner membrane-associated; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.969
BBta_5810
Malate dehydrogenase; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic.
  
 
 0.963
BBta_7568
Citrate synthase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; Belongs to the citrate synthase family.
 
 0.936
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.935
sdhD
Succinate dehydrogenase subunit D; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 6 : Inner membrane-associated.
  
 
 0.930
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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