STRINGSTRING
gppA gppA CKO_04137 CKO_04137 CKO_05107 CKO_05107 CKO_00286 CKO_00286 ppk ppk rhlB rhlB CKO_00123 CKO_00123 CKO_00308 CKO_00308 metG metG polA polA CKO_01969 CKO_01969
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
gppAHypothetical protein; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. (494 aa)    
Predicted Functional Partners:
CKO_04137
Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.934
CKO_05107
Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.921
CKO_00286
Hypothetical protein; KEGG: sty:STY2743 3.3e-259 ppx; exopolyphosphatase K01514; COG: COG0248 Exopolyphosphatase; Psort location: Cytoplasmic, score:8.96; Belongs to the GppA/Ppx family.
  
  
 
0.911
ppk
Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.897
rhlB
Hypothetical protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.
  
    0.816
CKO_00123
Hypothetical protein; KEGG: eci:UTI89_C4335 4.1e-55 trxA; thioredoxin 1 K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score:9.26; Belongs to the thioredoxin family.
       0.598
CKO_00308
Hypothetical protein; KEGG: eci:UTI89_C2806 3.8e-68 gcvR; glycine cleavage system transcriptional repressor K03567; COG: COG2716 Glycine cleavage system regulatory protein; Psort location: Cytoplasmic, score:9.97.
 
     0.481
metG
Hypothetical protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
  
 0.457
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.452
CKO_01969
Hypothetical protein; COG: COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; Psort location: Cytoplasmic, score:8.96.
 
 
   0.425
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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