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gpt gpt guaB guaB apt apt gmk gmk guaA guaA Jann_1804 Jann_1804 yaaF yaaF Jann_0205 Jann_0205 Jann_2344 Jann_2344 Jann_2961 Jann_2961 deoD deoD
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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textmining
co-expression
protein homology
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gptXanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (172 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.944
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.921
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.915
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.914
Jann_1804
Inosine/uridine-preferring nucleoside hydrolase.
    
 0.905
yaaF
Inosine/uridine-preferring nucleoside hydrolase.
    
 0.905
Jann_0205
Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.904
Jann_2344
MazG family protein.
     
 0.903
Jann_2961
5'-Nucleotidase-like protein; Belongs to the 5'-nucleotidase family.
     
 0.903
deoD
Purine-nucleoside phosphorylase.
    
  0.902
Your Current Organism:
Jannaschia sp. CCS1
NCBI taxonomy Id: 290400
Other names: J. sp. CCS1
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