STRINGSTRING
Jann_4208 Jann_4208 ubiE ubiE ubiG ubiG mutM mutM znuC znuC rpsT rpsT Jann_1242 Jann_1242 Jann_1509 Jann_1509 Jann_4211 Jann_4211 ubiA ubiA Jann_0425 Jann_0425
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jann_42082-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (509 aa)    
Predicted Functional Partners:
ubiE
2-octaprenyl-6-methoxy-1,4-benzoquinone methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
  
 0.813
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 0.779
mutM
DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.735
znuC
ABC transporter related protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
      0.613
rpsT
SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA.
  
    0.522
Jann_1242
Ubiquinone biosynthesis hydroxylase UbiH/UbiF/VisC/COQ6 family.
  
 
 0.462
Jann_1509
Beta-N-acetylhexosaminidase.
      
 0.444
Jann_4211
Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.434
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
 
 
 0.422
Jann_0425
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
  
 
 0.420
Your Current Organism:
Jannaschia sp. CCS1
NCBI taxonomy Id: 290400
Other names: J. sp. CCS1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.