STRINGSTRING
bioB bioB CTN_0462 CTN_0462 CTN_1304 CTN_1304 CTN_0443 CTN_0443 CTN_0290 CTN_0290 CTN_0288 CTN_0288 CTN_0485 CTN_0485 CTN_0760 CTN_0760 polA polA ribA ribA CTN_1067 CTN_1067
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (279 aa)    
Predicted Functional Partners:
CTN_0462
Biotin--(Acetyl-CoA carboxylase) synthetase.
  
 
 0.919
CTN_1304
Biotin synthetase.
  
  
 
0.913
CTN_0443
Radical SAM domain protein.
     
  0.900
CTN_0290
MazG-related protein.
       0.783
CTN_0288
Glycosyl transferase, group 1.
       0.572
CTN_0485
NADP-reducing hydrogenase, subunit D.
  
  
 0.503
CTN_0760
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.444
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.429
ribA
Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
      
 0.422
CTN_1067
Fe-hydrogenase alpha subunit.
  
  
 0.418
Your Current Organism:
Thermotoga neapolitana
NCBI taxonomy Id: 309803
Other names: T. neapolitana DSM 4359, Thermotoga neapolitana ATCC 49049, Thermotoga neapolitana DSM 4359, Thermotoga neapolitana JCM 10099, Thermotoga neapolitana NS-E
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