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nadD nadD nadK nadK pncB pncB cinA cinA nadE nadE nadC nadC cobB cobB SRU_2205 SRU_2205 SRU_2206 SRU_2206 SRU_2204 SRU_2204 SRU_2783 SRU_2783
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (195 aa)    
Predicted Functional Partners:
nadK
ATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.954
pncB
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 
 0.953
cinA
Competence/damage-inducible protein CinA; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.
  
 
 0.952
nadE
NAD(+) synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.950
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
    
 0.934
cobB
Transcriptional regulator, Sir2 family; Identified by match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily.
   
 0.934
SRU_2205
Conserved hypothetical protein.
     
 0.904
SRU_2206
Alanine dehydrogenase/PNT, N-terminal domain family; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222.
     
 0.904
SRU_2204
NAD(P) transhydrogenase beta subunit superfamily; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.902
SRU_2783
HAD superfamily (subfamily IG) hydrolase, 5'-nucleotidase, putative; Identified by match to protein family HMM PF05761; match to protein family HMM TIGR02244.
    
  0.902
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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