STRINGSTRING
trpF trpF trpB trpB trpC trpC trpA trpA trpD trpD trpEG trpEG pabB pabB Avi_0018 Avi_0018 folC folC accD-2 accD-2 ribD ribD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpFN-(5prime-phosphoribosyl) anthranilate isomerase; Belongs to the TrpF family. (224 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.999
trpC
Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpA
Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.998
trpEG
Anthranilate synthase components I and II.
  
 0.976
pabB
Para-aminobenzoate synthase component I.
 
  
 0.926
Avi_0018
Conserved hypothetical protein.
       0.685
folC
Folylpolyglutamate synthase.
     
 0.660
accD-2
Acetyl-coenzyme A carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
     
 0.646
ribD
Bifunctional riboflavin deaminase-reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.621
Your Current Organism:
Agrobacterium vitis
NCBI taxonomy Id: 311402
Other names: A. vitis S4, Agrobacterium vitis S4, Agrobacterium vitis str. S4, Agrobacterium vitis strain S4
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.