node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ELI_05430 | polA | ELI_05430 | ELI_14330 | COG0608 Single-stranded DNA-specific exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.583 |
ELI_05430 | ruvB | ELI_05430 | ELI_10425 | COG0608 Single-stranded DNA-specific exonuclease. | Holliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.416 |
ELI_05430 | ruvC | ELI_05430 | ELI_14520 | COG0608 Single-stranded DNA-specific exonuclease. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.522 |
ELI_11140 | polA | ELI_11140 | ELI_14330 | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.504 |
ELI_11140 | ruvA | ELI_11140 | ELI_10440 | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | Probable holliday junction DNA helicase protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.486 |
ELI_11140 | ruvC | ELI_11140 | ELI_14520 | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.592 |
ELI_11630 | ruvC | ELI_11630 | ELI_14520 | COG2852 Uncharacterized protein conserved in bacteria. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.695 |
ELI_14510 | ELI_14515 | ELI_14510 | ELI_14515 | Putative membrane protein. | Glucose-1-phosphate adenylyl transferase. | 0.585 |
ELI_14510 | ruvC | ELI_14510 | ELI_14520 | Putative membrane protein. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.481 |
ELI_14515 | ELI_14510 | ELI_14515 | ELI_14510 | Glucose-1-phosphate adenylyl transferase. | Putative membrane protein. | 0.585 |
ELI_14515 | ELI_14525 | ELI_14515 | ELI_14525 | Glucose-1-phosphate adenylyl transferase. | Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. | 0.438 |
ELI_14515 | ruvC | ELI_14515 | ELI_14520 | Glucose-1-phosphate adenylyl transferase. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.733 |
ELI_14525 | ELI_14515 | ELI_14525 | ELI_14515 | Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. | Glucose-1-phosphate adenylyl transferase. | 0.438 |
ELI_14525 | ruvC | ELI_14525 | ELI_14520 | Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.540 |
def | ruvC | ELI_02080 | ELI_14520 | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.476 |
polA | ELI_05430 | ELI_14330 | ELI_05430 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | COG0608 Single-stranded DNA-specific exonuclease. | 0.583 |
polA | ELI_11140 | ELI_14330 | ELI_11140 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.504 |
polA | ruvA | ELI_14330 | ELI_10440 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Probable holliday junction DNA helicase protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.489 |
polA | ruvB | ELI_14330 | ELI_10425 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.597 |
polA | ruvC | ELI_14330 | ELI_14520 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.662 |