node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RF_0114 | abcT1 | RF_0114 | RF_0115 | Unknown. | ABC transporter ATP-binding protein; Two ATP-biding cassettes. | 0.777 |
RF_0114 | kdsA | RF_0114 | RF_0113 | Unknown. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.673 |
abcT1 | RF_0114 | RF_0115 | RF_0114 | ABC transporter ATP-binding protein; Two ATP-biding cassettes. | Unknown. | 0.777 |
abcT1 | kdsA | RF_0115 | RF_0113 | ABC transporter ATP-binding protein; Two ATP-biding cassettes. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.669 |
kdsA | RF_0114 | RF_0113 | RF_0114 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | Unknown. | 0.673 |
kdsA | abcT1 | RF_0113 | RF_0115 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | ABC transporter ATP-binding protein; Two ATP-biding cassettes. | 0.669 |
kdsA | kdsB | RF_0113 | RF_0594 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.886 |
kdsA | kdtA | RF_0113 | RF_0072 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.738 |
kdsA | kpsF | RF_0113 | RF_0720 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | KpsF protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.995 |
kdsA | lpxK | RF_0113 | RF_0196 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.692 |
kdsA | manC | RF_0113 | RF_0241 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | Mannose-1-phosphate guanylyltransferase. | 0.799 |
kdsA | secA | RF_0113 | RF_0941 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.656 |
kdsA | smpB | RF_0113 | RF_0661 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches t [...] | 0.617 |
kdsA | trmU | RF_0113 | RF_0496 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.673 |
kdsB | kdsA | RF_0594 | RF_0113 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.886 |
kdsB | kdtA | RF_0594 | RF_0072 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.984 |
kdsB | kpsF | RF_0594 | RF_0720 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | KpsF protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.938 |
kdsB | lpxK | RF_0594 | RF_0196 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.815 |
kdsB | manC | RF_0594 | RF_0241 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Mannose-1-phosphate guanylyltransferase. | 0.508 |
kdtA | kdsA | RF_0072 | RF_0113 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.738 |