node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sden_0078 | Sden_1167 | Sden_0078 | Sden_1167 | CMP/dCMP deaminase, zinc-binding. | Thymidylate kinase-like protein. | 0.924 |
Sden_0078 | Sden_2137 | Sden_0078 | Sden_2137 | CMP/dCMP deaminase, zinc-binding. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.902 |
Sden_0078 | cdd | Sden_0078 | Sden_2288 | CMP/dCMP deaminase, zinc-binding. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.422 |
Sden_0078 | dut | Sden_0078 | Sden_0324 | CMP/dCMP deaminase, zinc-binding. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.944 |
Sden_0078 | tdk | Sden_0078 | Sden_2536 | CMP/dCMP deaminase, zinc-binding. | Thymidine kinase. | 0.934 |
Sden_0078 | thyA | Sden_0078 | Sden_2779 | CMP/dCMP deaminase, zinc-binding. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.940 |
Sden_0078 | tmk | Sden_0078 | Sden_2051 | CMP/dCMP deaminase, zinc-binding. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.935 |
Sden_1167 | Sden_0078 | Sden_1167 | Sden_0078 | Thymidylate kinase-like protein. | CMP/dCMP deaminase, zinc-binding. | 0.924 |
Sden_1167 | Sden_2137 | Sden_1167 | Sden_2137 | Thymidylate kinase-like protein. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.910 |
Sden_1167 | dut | Sden_1167 | Sden_0324 | Thymidylate kinase-like protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.933 |
Sden_1167 | tdk | Sden_1167 | Sden_2536 | Thymidylate kinase-like protein. | Thymidine kinase. | 0.928 |
Sden_1167 | thyA | Sden_1167 | Sden_2779 | Thymidylate kinase-like protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.928 |
Sden_1167 | tmk | Sden_1167 | Sden_2051 | Thymidylate kinase-like protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.900 |
Sden_2137 | Sden_0078 | Sden_2137 | Sden_0078 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | CMP/dCMP deaminase, zinc-binding. | 0.902 |
Sden_2137 | Sden_1167 | Sden_2137 | Sden_1167 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate kinase-like protein. | 0.910 |
Sden_2137 | Sden_3074 | Sden_2137 | Sden_3074 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.901 |
Sden_2137 | cdd | Sden_2137 | Sden_2288 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.920 |
Sden_2137 | deoA | Sden_2137 | Sden_1026 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.924 |
Sden_2137 | deoD | Sden_2137 | Sden_1028 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Purine-nucleoside phosphorylase. | 0.916 |
Sden_2137 | dut | Sden_2137 | Sden_0324 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |