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queC queC queE queE Mhun_2831 Mhun_2831 Mhun_2834 Mhun_2834 Mhun_2835 Mhun_2835 taw1 taw1 tgtA tgtA Mhun_1575 Mhun_1575 argS argS prf1 prf1 sepS sepS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (220 aa)    
Predicted Functional Partners:
queE
Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.999
Mhun_2831
6-pyruvoyl tetrahydropterin synthase and hypothetical protein.
 
  
 0.993
Mhun_2834
NUDIX hydrolase.
       0.799
Mhun_2835
Hypothetical protein.
       0.775
taw1
Radical SAM; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
     
 0.654
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
   
 0.632
Mhun_1575
Cupin 2, conserved barrel.
       0.615
argS
arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.585
prf1
Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
       0.568
sepS
phosphoserine-tRNA(Cys) ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
       0.568
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
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