STRINGSTRING
panC panC panB panB Caur_2859 Caur_2859 Caur_2002 Caur_2002 Caur_2042 Caur_2042 coaA coaA Caur_3356 Caur_3356 cmk cmk Caur_1718 Caur_1718 Caur_3362 Caur_3362 Caur_3652 Caur_3652
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.998
Caur_2859
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
 0.986
Caur_2002
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
Caur_2042
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
coaA
TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: pla:Plav_1229 pantothenate kinase.
     
 0.919
Caur_3356
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
cmk
KEGG: rrs:RoseRS_0324 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
      0.909
Caur_1718
PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_1738 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.903
Caur_3362
PFAM: aminotransferase class-III; KEGG: rca:Rcas_0117 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.903
Caur_3652
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.902
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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