STRINGSTRING
psmB1 psmB1 psmA psmA pan pan Saci_1501 Saci_1501 psmB2 psmB2 glpK1 glpK1 glpK2 glpK2 Saci_0766 Saci_0766 thsB thsB hisS hisS Saci_0664 Saci_0664
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
psmB1Proteasome protease subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (195 aa)    
Predicted Functional Partners:
psmA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.993
pan
Protease regulatory protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S pro [...]
  
 0.984
Saci_1501
Hypothetical protein; Similar to gi:15897071.
   
 0.917
psmB2
Proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
  
0.911
glpK1
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.853
glpK2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.853
Saci_0766
50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.788
thsB
Thermosome beta subunit; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
 
 
 0.784
hisS
Histidyl tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
   0.753
Saci_0664
Conserved Archaeal protein.
       0.696
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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