node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE03548.1 | hemA | Cphamn1_0589 | Cphamn1_0934 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cch:Cag_1730 pyruvate:ferredoxin (flavodoxin) oxidoreductase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.484 |
ACE03868.1 | ACE03877.1 | Cphamn1_0923 | Cphamn1_0932 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.880 |
ACE03868.1 | ACE04760.1 | Cphamn1_0923 | Cphamn1_1843 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: plt:Plut_0050 uroporphyrin-III C-methyltransferase-like. | 0.989 |
ACE03868.1 | ACE04761.1 | Cphamn1_0923 | Cphamn1_1844 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: siroheme synthase; KEGG: cte:CT2239 porphyrin biosynthesis protein, putative. | 0.582 |
ACE03868.1 | hemA | Cphamn1_0923 | Cphamn1_0934 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.841 |
ACE03868.1 | hemC | Cphamn1_0923 | Cphamn1_0933 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.994 |
ACE03868.1 | hemE | Cphamn1_0923 | Cphamn1_0287 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.680 |
ACE03868.1 | hemL | Cphamn1_0923 | Cphamn1_0202 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pvi:Cvib_1681 glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.991 |
ACE03877.1 | ACE03868.1 | Cphamn1_0932 | Cphamn1_0923 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.880 |
ACE03877.1 | ACE03880.1 | Cphamn1_0932 | Cphamn1_0935 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: cytochrome c assembly protein; KEGG: plt:Plut_1425 HemX protein, putative. | 0.641 |
ACE03877.1 | ACE04760.1 | Cphamn1_0932 | Cphamn1_1843 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: plt:Plut_0050 uroporphyrin-III C-methyltransferase-like. | 0.960 |
ACE03877.1 | ACE04761.1 | Cphamn1_0932 | Cphamn1_1844 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: siroheme synthase; KEGG: cte:CT2239 porphyrin biosynthesis protein, putative. | 0.422 |
ACE03877.1 | hemA | Cphamn1_0932 | Cphamn1_0934 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.926 |
ACE03877.1 | hemC | Cphamn1_0932 | Cphamn1_0933 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.997 |
ACE03877.1 | hemE | Cphamn1_0932 | Cphamn1_0287 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.932 |
ACE03877.1 | hemL | Cphamn1_0932 | Cphamn1_0202 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pvi:Cvib_1681 glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.622 |
ACE03880.1 | ACE03877.1 | Cphamn1_0935 | Cphamn1_0932 | PFAM: cytochrome c assembly protein; KEGG: plt:Plut_1425 HemX protein, putative. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.641 |
ACE03880.1 | hemA | Cphamn1_0935 | Cphamn1_0934 | PFAM: cytochrome c assembly protein; KEGG: plt:Plut_1425 HemX protein, putative. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.555 |
ACE03880.1 | hemC | Cphamn1_0935 | Cphamn1_0933 | PFAM: cytochrome c assembly protein; KEGG: plt:Plut_1425 HemX protein, putative. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.508 |
ACE04760.1 | ACE03868.1 | Cphamn1_1843 | Cphamn1_0923 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: plt:Plut_0050 uroporphyrin-III C-methyltransferase-like. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pvi:Cvib_1252 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.989 |