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hemL hemL ABE75537.1 ABE75537.1 hemA hemA hemC hemC ABE75105.1 ABE75105.1 ABE74298.1 ABE74298.1 cysG cysG ABE75891.1 ABE75891.1 ABE76048.1 ABE76048.1 hemE hemE ABE73963.1 ABE73963.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemLGlutamate-1-semialdehyde 2,1-aminomutase. (433 aa)    
Predicted Functional Partners:
ABE75537.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.991
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.989
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.948
ABE75105.1
uroporphyrinogen-III C-methyltransferase.
 
   
 0.815
ABE74298.1
[Acyl-carrier-protein] S-malonyltransferase.
    
 0.741
cysG
Precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
   
 0.714
ABE75891.1
Conserved hypothetical protein.
   
 
 0.631
ABE76048.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.605
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.592
ABE73963.1
Putative phosphomethylpyrimidine kinase.
 
  
 0.588
Your Current Organism:
Psychrobacter cryohalolentis
NCBI taxonomy Id: 335284
Other names: P. cryohalolentis K5, Psychrobacter cryohalolentis K5, Psychrobacter cryohalolentis str. K5, Psychrobacter cryohalolentis strain K5
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