node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Swol_0099 | Swol_0100 | Swol_0099 | Swol_0100 | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | KEGG: mta:Moth_0140 NADP oxidoreductase, coenzyme F420-dependent. | 0.576 |
Swol_0099 | birA | Swol_0099 | Swol_0775 | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.692 |
Swol_0099 | ilvE | Swol_0099 | Swol_2148 | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.407 |
Swol_0099 | panB | Swol_0099 | Swol_0101 | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.582 |
Swol_0099 | panC | Swol_0099 | Swol_0102 | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.519 |
Swol_0100 | Swol_0099 | Swol_0100 | Swol_0099 | KEGG: mta:Moth_0140 NADP oxidoreductase, coenzyme F420-dependent. | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.576 |
Swol_0100 | panB | Swol_0100 | Swol_0101 | KEGG: mta:Moth_0140 NADP oxidoreductase, coenzyme F420-dependent. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.903 |
Swol_0100 | panC | Swol_0100 | Swol_0102 | KEGG: mta:Moth_0140 NADP oxidoreductase, coenzyme F420-dependent. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.944 |
Swol_0100 | panD | Swol_0100 | Swol_0103 | KEGG: mta:Moth_0140 NADP oxidoreductase, coenzyme F420-dependent. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.575 |
Swol_0107 | birA | Swol_0107 | Swol_0775 | KEGG: pca:Pcar_1972 nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.545 |
Swol_0107 | panB | Swol_0107 | Swol_0101 | KEGG: pca:Pcar_1972 nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.728 |
Swol_1181 | birA | Swol_1181 | Swol_0775 | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.529 |
Swol_1181 | panB | Swol_1181 | Swol_0101 | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.931 |
Swol_1181 | panC | Swol_1181 | Swol_0102 | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.928 |
birA | Swol_0099 | Swol_0775 | Swol_0099 | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.692 |
birA | Swol_0107 | Swol_0775 | Swol_0107 | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | KEGG: pca:Pcar_1972 nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.545 |
birA | Swol_1181 | Swol_0775 | Swol_1181 | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.529 |
birA | guaA | Swol_0775 | Swol_1784 | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.667 |
birA | ilvE | Swol_0775 | Swol_2148 | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.544 |
birA | panB | Swol_0775 | Swol_0101 | Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.725 |