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Rfer_0455 Rfer_0455 Rfer_0454 Rfer_0454 leuA leuA Rfer_0262 Rfer_0262 Rfer_4205 Rfer_4205 glcB glcB Rfer_2974 Rfer_2974 Rfer_0880 Rfer_0880 Rfer_0986 Rfer_0986 Rfer_1025 Rfer_1025 Rfer_2866 Rfer_2866
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
Rfer_0455Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (306 aa)    
Predicted Functional Partners:
Rfer_0454
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.999
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.990
Rfer_0262
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.938
Rfer_4205
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.922
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
  
  0.913
Rfer_2974
Phosphate butyryltransferase.
    
 0.909
Rfer_0880
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Rfer_0986
Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Rfer_1025
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Rfer_2866
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Your Current Organism:
Rhodoferax ferrireducens
NCBI taxonomy Id: 338969
Other names: Albidiferax ferrireducens T118, R. ferrireducens T118, Rhodoferax ferrireducens ATCC BAA-621, Rhodoferax ferrireducens DSM 15236, Rhodoferax ferrireducens T118, Rhodoferax ferrireducens str. T118, Rhodoferax ferrireducens strain T118
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