node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rfer_0262 | Rfer_0455 | Rfer_0262 | Rfer_0455 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.938 |
Rfer_0262 | Rfer_0880 | Rfer_0262 | Rfer_0880 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.846 |
Rfer_0262 | Rfer_0986 | Rfer_0262 | Rfer_0986 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.846 |
Rfer_0262 | Rfer_1025 | Rfer_0262 | Rfer_1025 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.846 |
Rfer_0262 | Rfer_2974 | Rfer_0262 | Rfer_2974 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Phosphate butyryltransferase. | 0.922 |
Rfer_0262 | Rfer_4205 | Rfer_0262 | Rfer_4205 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.840 |
Rfer_0262 | glcB | Rfer_0262 | Rfer_3581 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.972 |
Rfer_0262 | leuA | Rfer_0262 | Rfer_2345 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.906 |
Rfer_0454 | Rfer_0455 | Rfer_0454 | Rfer_0455 | Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.999 |
Rfer_0454 | Rfer_4205 | Rfer_0454 | Rfer_4205 | Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.405 |
Rfer_0455 | Rfer_0262 | Rfer_0455 | Rfer_0262 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.938 |
Rfer_0455 | Rfer_0454 | Rfer_0455 | Rfer_0454 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.999 |
Rfer_0455 | Rfer_0880 | Rfer_0455 | Rfer_0880 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.908 |
Rfer_0455 | Rfer_0986 | Rfer_0455 | Rfer_0986 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.908 |
Rfer_0455 | Rfer_1025 | Rfer_0455 | Rfer_1025 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.908 |
Rfer_0455 | Rfer_2866 | Rfer_0455 | Rfer_2866 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.908 |
Rfer_0455 | Rfer_2974 | Rfer_0455 | Rfer_2974 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Phosphate butyryltransferase. | 0.909 |
Rfer_0455 | Rfer_4205 | Rfer_0455 | Rfer_4205 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.922 |
Rfer_0455 | glcB | Rfer_0455 | Rfer_3581 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.913 |
Rfer_0455 | leuA | Rfer_0455 | Rfer_2345 | Semialdehyde dehydrogenase, NAD - binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.990 |