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Pars_0075 Pars_0075 Pars_0653 Pars_0653 Pars_2202 Pars_2202 Pars_2356 Pars_2356 Pars_0063 Pars_0063 Pars_1717 Pars_1717 gch3 gch3 moaA moaA Pars_0074 Pars_0074 Pars_2122 Pars_2122 lig lig
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Pars_0075TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: pis:Pisl_1114 putative adenylyl cyclase CyaB. (176 aa)    
Predicted Functional Partners:
Pars_0653
PFAM: nucleoside diphosphate kinase; KEGG: pai:PAE1561 nucleoside diphosphate kinase.
    
  0.902
Pars_2202
PFAM: NUDIX hydrolase; KEGG: pis:Pisl_0088 NUDIX hydrolase.
    
 0.902
Pars_2356
PFAM: NUDIX hydrolase; KEGG: pai:PAE0714 diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (MutT/NUDIX family protein).
    
 0.902
Pars_0063
PFAM: pyruvate kinase; KEGG: pai:PAE0819 pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.900
Pars_1717
Protein of unknown function DUF265; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
     
  0.900
gch3
GTP cyclohydrolase IIa; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
  
  
  0.837
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
  0.816
Pars_0074
KEGG: pai:PAE0831 hypothetical protein.
       0.805
Pars_2122
PFAM: GTP cyclohydrolase I; KEGG: pai:PAE1588 GTP cyclohydrolase I.
     
  0.800
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
       0.787
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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