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ppcA ppcA Pars_1571 Pars_1571 Pars_0510 Pars_0510 Pars_0515 Pars_0515 Pars_1008 Pars_1008 Pars_1445 Pars_1445 Pars_0063 Pars_0063 eno eno Pars_0511 Pars_0511 Pars_0954 Pars_0954 Pars_1035 Pars_1035
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (460 aa)    
Predicted Functional Partners:
Pars_1571
PFAM: Lactate/malate dehydrogenase; KEGG: pai:PAE2370 malate dehydrogenase; Belongs to the LDH/MDH superfamily.
     
 0.919
Pars_0510
Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; KEGG: pis:Pisl_1888 phosphoenolpyruvate synthase.
     
 0.913
Pars_0515
PFAM: PEP-utilising enzyme, mobile region; KEGG: rxy:Rxyl_1575 PEP-utilising enzyme, mobile region.
     
 0.913
Pars_1008
KEGG: pai:PAE3383 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region.
     
 0.913
Pars_1445
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.913
Pars_0063
PFAM: pyruvate kinase; KEGG: pai:PAE0819 pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.905
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
  0.900
Pars_0511
PFAM: PEP-utilising enzyme, mobile region; KEGG: gme:Gmet_2100 hypothetical protein.
     
  0.900
Pars_0954
Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: pai:PAE2662 formate dehydrogenase alpha subunit.
  
  
  0.899
Pars_1035
KEGG: pai:PAE3584 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
     
 0.829
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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