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acsA acsA Cag_0797 Cag_0797 Cag_1730 Cag_1730 Cag_0317 Cag_0317 Cag_0366 Cag_0366 Cag_1754 Cag_1754 Cag_0359 Cag_0359 Cag_1898 Cag_1898 Cag_0796 Cag_0796 Cag_1229 Cag_1229 leuA leuA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (666 aa)    
Predicted Functional Partners:
Cag_0797
ATP citrate lyase subunit 2.
  
 0.976
Cag_1730
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.959
Cag_0317
Citrate synthase; Belongs to the citrate synthase family.
  
 0.955
Cag_0366
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.944
Cag_1754
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.940
Cag_0359
Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.924
Cag_1898
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.917
Cag_0796
ATP citrate lyase subunit 1.
   
 
 0.915
Cag_1229
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.915
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.915
Your Current Organism:
Chlorobium chlorochromatii
NCBI taxonomy Id: 340177
Other names: C. chlorochromatii CaD3, Chlorobium chlorochromatii CaD3, Chlorobium chlorochromatii str. CaD3, Chlorobium chlorochromatii strain CaD3
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