STRINGSTRING
folE folE folK folK queD queD ribA ribA folP folP folB folB nudB nudB ndk ndk mazG mazG pykA pykA SG1438 SG1438
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP cyclohydrolase I. (221 aa)    
Predicted Functional Partners:
folK
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 0.997
queD
Putative 6-pyruvoyl tetrahydrobiopterin synthase.
  
 
 0.983
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
 
 
 
 0.982
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.976
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.956
nudB
dATP pyrophosphohydrolase.
    
  0.911
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.837
mazG
Conserved hypothetical protein.
    
 0.826
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
    
  0.805
SG1438
Pyruvate kinase I; Belongs to the pyruvate kinase family.
    
  0.805
Your Current Organism:
Sodalis glossinidius
NCBI taxonomy Id: 343509
Other names: S. glossinidius str. 'morsitans', Sodalis glossinidius str. 'morsitans'
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.