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pyrF pyrF pyrE pyrE pyrH pyrH upp upp surE surE udk udk carB carB ushA ushA ACD08124.1 ACD08124.1 yjjG yjjG ACD07314.1 ACD07314.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.991
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.938
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.938
surE
Multifunctional protein SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
    
 0.919
udk
Uridine kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00235.
  
 0.916
carB
Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family.
 
  
 0.910
ushA
UDP-sugar hydrolase/5'-nucleotidase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family.
    
  0.901
ACD08124.1
HAD hydrolase, IA family; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509.
  
 
  0.901
yjjG
5-nucleotidase YjjG; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254.
  
 
  0.901
ACD07314.1
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
     
  0.900
Your Current Organism:
Shigella boydii
NCBI taxonomy Id: 344609
Other names: S. boydii CDC 3083-94, Shigella boydii BS512, Shigella boydii CDC 3083-94, Shigella boydii str. CDC 3083-94, Shigella boydii strain CDC 3083-94
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