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cobT cobT Dred_1910 Dred_1910 cbiA cbiA cobS cobS cobQ cobQ cobD cobD cbiA-2 cbiA-2 Dred_2733 Dred_2733 Dred_1908 Dred_1908 Dred_2702 Dred_2702 Dred_3256 Dred_3256
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (351 aa)    
Predicted Functional Partners:
Dred_1910
Adenosylcobinamide kinase; PFAM: cobalbumin biosynthesis enzyme; KEGG: mta:Moth_1087 cobalbumin biosynthesis enzyme.
  
 0.996
cbiA
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.972
cobS
Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.971
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.924
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.913
cbiA-2
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.875
Dred_2733
TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: cno:NT01CX_1331 cobalt transport protein.
  
  
 0.869
Dred_1908
PFAM: Phosphoglycerate mutase; KEGG: mta:Moth_1105 phosphoglycerate/bisphosphoglycerate mutase; Belongs to the phosphoglycerate mutase family.
  
 0.808
Dred_2702
PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: mta:Moth_1103 GHMP kinase.
  
  
 0.801
Dred_3256
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mva:Mvan_5590 alcohol dehydrogenase GroES domain protein.
      0.768
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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