STRINGSTRING
psmB psmB psmA psmA Mthe_0792 Mthe_0792 pan pan pan-2 pan-2 rpl40e rpl40e Mthe_0082 Mthe_0082 Mthe_0190 Mthe_0190 Mthe_0077 Mthe_0077 Mthe_0531 Mthe_0531 Mthe_0613 Mthe_0613
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
psmBProteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (207 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
Mthe_0792
Proteasome Rpn11 subunit JAMM motif, Metallo peptidase, MEROPS family M67B; KEGG: mac:MA1736 Mov34 family protein.
   
 0.927
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.906
pan-2
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.906
rpl40e
KEGG: mba:Mbar_A0674 ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.871
Mthe_0082
PFAM: beta-lactamase domain protein; KH, type 1, domain protein; RNA-metabolising metallo-beta-lactamase; SMART: KH domain protein; KEGG: mma:MM0695 cleavage and polyadenylation specificity factor 100 kD subunit.
     
 0.847
Mthe_0190
PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: mma:MM0854 cell division cycle protein 48 homolog.
  
 0.765
Mthe_0077
AAA family ATPase, CDC48 subfamily; KEGG: nph:NP3072A AAA-type ATPase (transitional ATPase homolog); TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
  
 0.764
Mthe_0531
KEGG: afu:AF1297 cell division control protein 48, AAA family (cdc48-1); TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
  
 0.764
Mthe_0613
KEGG: mma:MM1256 CdcH protein; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
  
 0.764
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
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