STRINGSTRING
pckG pckG Mflv_4198 Mflv_4198 Mflv_2616 Mflv_2616 mdh mdh ppc ppc Mflv_1729 Mflv_1729 Mflv_0262 Mflv_0262 Mflv_3591 Mflv_3591 mqo mqo eno eno Mflv_1726 Mflv_1726
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (609 aa)    
Predicted Functional Partners:
Mflv_4198
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.976
Mflv_2616
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmc:Mmcs_3567 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
   
 
 0.965
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
 
  
 0.960
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.959
Mflv_1729
KEGG: mmc:Mmcs_4456 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.939
Mflv_0262
PFAM: pyruvate kinase; KEGG: mva:Mvan_0632 pyruvate kinase.
  
 
 0.932
Mflv_3591
PFAM: pyruvate kinase; KEGG: mmc:Mmcs_3042 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.932
mqo
Malate--quinone oxidoreductase; KEGG: mmc:Mmcs_2069 malate dehydrogenase (acceptor); TIGRFAM: malate--quinone oxidoreductase; PFAM: FAD dependent oxidoreductase; Malate:quinone-oxidoreductase.
   
 
 0.923
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.916
Mflv_1726
PFAM: Citrate synthase; KEGG: mva:Mvan_5025 citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.914
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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