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Mflv_1124 Mflv_1124 Mflv_1125 Mflv_1125 Mflv_1129 Mflv_1129 Mflv_1126 Mflv_1126 Mflv_1127 Mflv_1127 Mflv_0107 Mflv_0107 Mflv_1128 Mflv_1128 mscL mscL Mflv_1133 Mflv_1133
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mflv_1124Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (160 aa)    
Predicted Functional Partners:
Mflv_1125
KEGG: mva:Mvan_5681 conserved hypothetical protein.
       0.773
Mflv_1129
KEGG: mva:Mvan_5677 conserved hypothetical protein.
       0.745
Mflv_1126
PFAM: copper resistance D domain protein; KEGG: mva:Mvan_5680 copper resistance D domain protein.
       0.664
Mflv_1127
PFAM: copper resistance protein CopC; KEGG: mva:Mvan_5679 copper resistance protein CopC.
       0.625
Mflv_0107
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: mva:Mvan_0801 isocitrate lyase.
 
  
 0.620
Mflv_1128
KEGG: mva:Mvan_5678 conserved hypothetical protein.
       0.506
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
  
 0.419
Mflv_1133
KEGG: mva:Mvan_5673 conserved hypothetical protein.
       0.410
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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