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hemA hemA hemC hemC hemL hemL Mvan_0846 Mvan_0846 Mvan_0847 Mvan_0847 gltX gltX gluQ gluQ Mvan_2305 Mvan_2305 hemE hemE Mvan_4109 Mvan_4109 Mvan_0850 Mvan_0850
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hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (456 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.998
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: mmc:Mmcs_0690 glutamate-1-semialdehyde-2,1-aminomutase.
 
 0.997
Mvan_0846
uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: mmc:Mmcs_0678 uroporphyrinogen III synthase HEM4.
 
  
 0.991
Mvan_0847
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mmc:Mmcs_0679 porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.988
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.976
gluQ
Glutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
     
 0.965
Mvan_2305
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmc:Mmcs_2074 uroporphyrin-III C-methyltransferase.
 
  
 0.908
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.872
Mvan_4109
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmc:Mmcs_4865 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
   
   0.751
Mvan_0850
KEGG: mmc:Mmcs_0682 putative conserved transmembrane protein.
  
    0.716
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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