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fumC fumC Acel_1865 Acel_1865 Acel_0387 Acel_0387 Acel_1658 Acel_1658 Acel_1864 Acel_1864 Acel_1647 Acel_1647 Acel_0115 Acel_0115 sucC sucC Acel_1956 Acel_1956 argH argH Acel_0292 Acel_0292
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (472 aa)    
Predicted Functional Partners:
Acel_1865
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: sco:SCO5107 putative succinate dehydrogenase flavoprotein subunit.
 
 0.994
Acel_0387
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.963
Acel_1658
KEGG: mbo:Mb1162 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.963
Acel_1864
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: nfa:nfa56030 putative succinate dehydrogenase iron-sulfur subunit.
  
 0.962
Acel_1647
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rba:RB307 NAD-dependent malic enzyme.
  
 
 0.948
Acel_0115
PFAM: Citrate synthase; KEGG: sco:SCO4388 citrate synthase; Belongs to the citrate synthase family.
   
 0.908
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.827
Acel_1956
PFAM: aldehyde dehydrogenase; KEGG: sma:SAV7134 putative aldehyde dehydrogenase.
   
 0.823
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fra:Francci3_3168 argininosuccinate lyase.
   
 
0.820
Acel_0292
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: sco:SCO4645 aspartate aminotransferase.
   
 0.819
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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