STRINGSTRING
Csac_0117 Csac_0117 Csac_0931 Csac_0931 Csac_0118 Csac_0118 spoIIAB spoIIAB Csac_0999 Csac_0999 Csac_1212 Csac_1212 Csac_2332 Csac_2332 Csac_0933 Csac_0933 Csac_1900 Csac_1900 Csac_2118 Csac_2118 Csac_2134 Csac_2134
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Csac_0117Phosphoprotein phosphatase; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (768 aa)    
Predicted Functional Partners:
Csac_0931
Peptidase U4, sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.937
Csac_0118
TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein.
 
   
 0.932
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.892
Csac_0999
Hypothetical protein.
  
   
 0.875
Csac_1212
Hypothetical protein.
  
   
 0.867
Csac_2332
PFAM: Stage II sporulation P family protein.
  
   
 0.865
Csac_0933
RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.864
Csac_1900
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.858
Csac_2118
TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein.
 
   
 0.846
Csac_2134
SMART: AAA ATPase.
  
   
 0.837
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
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