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hemC hemC Csac_1652 Csac_1652 Csac_1653 Csac_1653 hemA hemA hemL hemL Csac_1650 Csac_1650 Csac_2695 Csac_2695 Csac_0432 Csac_0432 nadE nadE xseB xseB Csac_0225 Csac_0225
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (290 aa)    
Predicted Functional Partners:
Csac_1652
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family.
 0.999
Csac_1653
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.999
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.998
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III.
  
 0.988
Csac_1650
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein.
 
  
 0.874
Csac_2695
Uroporphyrinogen-III decarboxylase-like protein; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.620
Csac_0432
Hypothetical protein.
  
 
 0.596
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.533
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
   
    0.527
Csac_0225
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein.
  
  
 0.443
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
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