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nusB nusB rpsJ rpsJ ribH1 ribH1 nusA nusA rpoZ rpoZ nusG nusG rpoC rpoC rpoA rpoA ribD ribD ribH-2 ribH-2 rpoB rpoB
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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nusBAntitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (171 aa)    
Predicted Functional Partners:
rpsJ
Ribosomal protein S10:Ribosomal protein S10, bacterial form; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 
 0.982
ribH1
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.977
nusA
Ribosomal protein S1:RNA binding S1:KH domain:KH domain, type 1; Participates in both transcription termination and antitermination.
 
 
 0.959
rpoZ
RNA polymerase, omega subunit:RNA polymerase Rpb6; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 0.939
nusG
Bacterial transcription antitermination protein NusG:KOW:NGN:KOW (Kyprides, Ouzounis, Woese) motif; Participates in transcription elongation, termination and antitermination.
  
 
 0.935
rpoC
RNA polymerase, alpha subunit:RNA polymerase I subunit A, N-terminal:RNA polymerase Rpb1, domain 1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.886
rpoA
RNA polymerase, alpha chain, bacterial and organelle; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.884
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.870
ribH-2
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. The isozyme RibH2 but not RibH1 is essential for Brucella intracellular survival and replication inside macrophages or in mice. Displays low catalytic activity in comparison with the isozyme RibH1. Is a highly immunogenic protein. Activates dendritic cells (DCs) in vitro, increasing the levels of costimulatory molecules and the sec [...]
  
  
 0.866
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.861
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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