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trpD trpD trpC trpC BAB1_1586 BAB1_1586 BAB2_0079 BAB2_0079 trpF trpF trpB trpB trpA trpA moaC moaC BAB2_0015 BAB2_0015 aroC aroC pheA pheA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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trpDGlycosyl transferase, family 3:Anthranilate phosphoribosyl transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.999
BAB1_1586
Anthranilate synthase; Glutamine amidotransferase class-I:Carbamoyl-phosphate synthase, GATase domain:Anthranilate synthase component I and chorisma.
 0.999
BAB2_0079
Anthranilate synthase component I and chorismate binding protein.
 0.999
trpF
N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family.
 
 
 0.998
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.997
trpA
Tryptophan synthase, alpha chain:FMN/related compound-binding core; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.991
moaC
Molybdopterin cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
     
 0.837
BAB2_0015
Isochorismate synthase:Anthranilate synthase component I and chorismate binding protein.
  
  
 0.832
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.819
pheA
Prephenate dehydratase:Amino acid-binding ACT.
 
 
 0.815
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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