STRINGSTRING
BAB2_0652 BAB2_0652 BAB1_0346 BAB1_0346 BAB1_1671 BAB1_1671 BAB1_0507 BAB1_0507 BAB1_0220 BAB1_0220 BAB1_1673 BAB1_1673 BAB2_0041 BAB2_0041 BAB1_0328 BAB1_0328 pdhS pdhS divK divK BAB1_0640 BAB1_0640
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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BAB2_0652PAS domain:PAS-associated C-terminal domain:PAC motif; Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection of the next host (By similarity). This photoreceptor protein is directly related to the bacterium's survival and replication within host macrophages, as it is required for optimal replication of bacteria inside macrophages. (463 aa)    
Predicted Functional Partners:
BAB1_0346
Na+/solute symporter:Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sen.
  
 0.984
BAB1_1671
Response regulator receiver.
 
 0.969
BAB1_0507
PAS domain:GGDEF:PAS-associated C-terminal domain:PAC motif:EAL domain.
 0.949
BAB1_0220
PAS domain:GGDEF:PAS-associated C-terminal domain:PAC motif:EAL domain.
 
 0.946
BAB1_1673
ATP-binding region, ATPase-like:Histidine kinase.
  
 0.941
BAB2_0041
Bacterial regulatory protein, LuxR family:Response regulator receiver.
 
 
 0.853
BAB1_0328
ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sensor protein, C-terminal:Histidine kinase.
  
 0.852
pdhS
Cell-division control histidine kinase PdhS; Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle (By similarity).
  
 0.851
divK
Response regulator receiver; Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS (By similarity).
  
 0.839
BAB1_0640
PAS domain:PAC motif:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Bacterial sensor protein, C-terminal:Hist.
  
 0.830
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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