node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAV1972 | fumA | BAV1972 | BAV0711 | Putative mercuric ion reductase. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.446 |
BAV1972 | gcvH | BAV1972 | BAV0492 | Putative mercuric ion reductase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.972 |
BAV1972 | gcvP | BAV1972 | BAV0493 | Putative mercuric ion reductase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.952 |
BAV1972 | gcvT | BAV1972 | BAV0491 | Putative mercuric ion reductase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.945 |
BAV1972 | glyA | BAV1972 | BAV2961 | Putative mercuric ion reductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
BAV1972 | lpdA | BAV1972 | BAV1665 | Putative mercuric ion reductase. | Dihydrolipoamide dehydrogenase. | 0.982 |
BAV1972 | odhL | BAV1972 | BAV1205 | Putative mercuric ion reductase. | Dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex). | 0.921 |
fumA | BAV1972 | BAV0711 | BAV1972 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative mercuric ion reductase. | 0.446 |
fumA | gcvP | BAV0711 | BAV0493 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.975 |
fumA | glyA | BAV0711 | BAV2961 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.535 |
fumA | lpdA | BAV0711 | BAV1665 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Dihydrolipoamide dehydrogenase. | 0.591 |
fumA | odhL | BAV0711 | BAV1205 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex). | 0.446 |
gcvH | BAV1972 | BAV0492 | BAV1972 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative mercuric ion reductase. | 0.972 |
gcvH | gcvP | BAV0492 | BAV0493 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | BAV0492 | BAV0491 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH | glyA | BAV0492 | BAV2961 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.971 |
gcvH | lpdA | BAV0492 | BAV1665 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase. | 0.995 |
gcvH | odhL | BAV0492 | BAV1205 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex). | 0.981 |
gcvH | purL | BAV0492 | BAV1546 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Phosphoribosylformylglycinamidine synthase; Start codon not provided; In the N-terminal section; belongs to the FGAMS family. | 0.461 |
gcvP | BAV1972 | BAV0493 | BAV1972 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative mercuric ion reductase. | 0.952 |