STRINGSTRING
gcvP gcvP gcvT gcvT gcvH gcvH glyA glyA lpdA lpdA purD purD purL purL fumA fumA ltaE ltaE odhL odhL BAV1972 BAV1972
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gcvPGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (955 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.998
lpdA
Dihydrolipoamide dehydrogenase.
 
 
 0.989
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.981
purL
Phosphoribosylformylglycinamidine synthase; Start codon not provided; In the N-terminal section; belongs to the FGAMS family.
  
  
 0.980
fumA
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
    0.975
ltaE
Low-specificity L-threonine aldolase.
    
 0.964
odhL
Dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex).
 
 
 0.959
BAV1972
Putative mercuric ion reductase.
  
 
 0.952
Your Current Organism:
Bordetella avium
NCBI taxonomy Id: 360910
Other names: B. avium 197N, Bordetella avium 197N, Bordetella avium str. 197N, Bordetella avium strain 197N
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