STRINGSTRING
folE folE Smed_1532 Smed_1532 Smed_1534 Smed_1534 Smed_1533 Smed_1533 ribB ribB Smed_2977 Smed_2977 moaA moaA ndk ndk MazG MazG Smed_2656 Smed_2656 Smed_2885 Smed_2885
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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[Homology]
Score
folEPFAM: GTP cyclohydrolase I; KEGG: sme:SMc01005 probable GTP cyclohydrolase I protein. (205 aa)    
Predicted Functional Partners:
Smed_1532
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sme:SMc00465 probable 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase protein.
  
 0.997
Smed_1534
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 0.984
Smed_1533
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.969
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.948
Smed_2977
PFAM: Alkaline phosphatase; KEGG: sme:SMc03243 putative alkaline phosphatase transmembrane protein.
    
 0.933
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.906
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.842
MazG
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: sme:SMc01051 MazG protein.
    
 0.828
Smed_2656
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc03985 probable adenylate/guanylate cyclase protein.
   
  0.815
Smed_2885
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc03099 putative adenylate cyclase protein.
   
  0.815
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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