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hmgA hmgA Smed_2836 Smed_2836 Smed_2831 Smed_2831 Smed_2832 Smed_2832 Smed_2834 Smed_2834 Smed_1692 Smed_1692 PhhB PhhB Smed_2404 Smed_2404 Smed_0197 Smed_0197
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (453 aa)    
Predicted Functional Partners:
Smed_2836
TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc03211 putative 4-hydroxyphenylpyruvate dioxygenase protein.
 
 0.997
Smed_2831
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: sme:SMc03206 maleylacetoacetate isomerase (glutathione transferase ZETA 1) protein.
 
 
 0.994
Smed_2832
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMc03207 putative aromatic amino acid degradation protein.
 
  
 0.918
Smed_2834
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: sme:SMc03209 putative transcription regulator protein.
 
     0.882
Smed_1692
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMc04240 hypothetical protein.
  
  
 0.740
PhhB
PFAM: transcriptional coactivator/pterin dehydratase; KEGG: sme:SMc03834 putative pterin-4-alpha-carbinolamine dehydratase protein.
  
  
 0.677
Smed_2404
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01961 hypothetical protein.
     
 0.444
Smed_0197
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein.
  
  
 0.425
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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