STRINGSTRING
ABN58102.1 ABN58102.1 pcn pcn lig lig fen fen ABN57692.1 ABN57692.1 ABN57712.1 ABN57712.1 ABN57369.1 ABN57369.1 ABN56731.1 ABN56731.1 polB polB ABN57546.1 ABN57546.1 ABN57545.1 ABN57545.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABN58102.1KEGG: det:DET0850 hypothetical protein. (197 aa)    
Predicted Functional Partners:
pcn
Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
 0.973
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.956
fen
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]
  
 0.924
ABN57692.1
PFAM: PHP C-terminal domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding, class 1; KEGG: mtp:Mthe_1315 PHP C-terminal domain protein.
  
 0.844
ABN57712.1
PFAM: PHP C-terminal domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; KEGG: mtp:Mthe_1315 PHP C-terminal domain protein.
  
 0.844
ABN57369.1
PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.818
ABN56731.1
PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mhu:Mhun_1156 DNA polymerase B region.
  
 0.794
polB
DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
   
 
 0.722
ABN57546.1
PFAM: SMC domain protein; KEGG: mtp:Mthe_1484 SMC domain protein.
  
 0.714
ABN57545.1
PFAM: metallophosphoesterase; KEGG: mtp:Mthe_1483 metallophosphoesterase.
  
 0.698
Your Current Organism:
Methanoculleus marisnigri
NCBI taxonomy Id: 368407
Other names: M. marisnigri JR1, Methanoculleus marisnigri JR1, Methanoculleus marisnigri str. JR1, Methanoculleus marisnigri strain JR1
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