node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCI_0126 | dapF | BCI_0126 | BCI_0125 | Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.542 |
BCI_0126 | hisB | BCI_0126 | BCI_0402 | Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Identified by match to protein family HMM PF00475; match to protein family HMM TIGR01261; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.453 |
BCI_0126 | ribD | BCI_0126 | BCI_0601 | Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.955 |
aspC | dapF | BCI_0407 | BCI_0125 | Aspartate aminotransferase; Identified by match to protein family HMM PF00155. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.514 |
carB | dapF | BCI_0560 | BCI_0125 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.880 |
carB | hisB | BCI_0560 | BCI_0402 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Identified by match to protein family HMM PF00475; match to protein family HMM TIGR01261; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.458 |
carB | ribD | BCI_0560 | BCI_0601 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.602 |
cysJ | dapF | BCI_0218 | BCI_0125 | Sulfite reductase [NADPH] flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.600 |
cysJ | ribD | BCI_0218 | BCI_0601 | Sulfite reductase [NADPH] flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.458 |
dapF | BCI_0126 | BCI_0125 | BCI_0126 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. | 0.542 |
dapF | aspC | BCI_0125 | BCI_0407 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate aminotransferase; Identified by match to protein family HMM PF00155. | 0.514 |
dapF | carB | BCI_0125 | BCI_0560 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | 0.880 |
dapF | cysJ | BCI_0125 | BCI_0218 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Sulfite reductase [NADPH] flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.600 |
dapF | hisB | BCI_0125 | BCI_0402 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Identified by match to protein family HMM PF00475; match to protein family HMM TIGR01261; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.523 |
dapF | hisD | BCI_0125 | BCI_0404 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.469 |
dapF | murE | BCI_0125 | BCI_0523 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.938 |
dapF | nudE | BCI_0125 | BCI_0014 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | ADP compounds hydrolase NudE; Identified by similarity to SP:P45799; match to protein family HMM PF00293. | 0.469 |
dapF | nudH | BCI_0125 | BCI_0542 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.671 |
dapF | ribD | BCI_0125 | BCI_0601 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.590 |
hisB | BCI_0126 | BCI_0402 | BCI_0126 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Identified by match to protein family HMM PF00475; match to protein family HMM TIGR01261; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. | 0.453 |