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acsA acsA gltA gltA glcB glcB ald ald ald-2 ald-2 mmsA mmsA RD1_0025 RD1_0025 bktB bktB phbA phbA fadA fadA ackA ackA
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (640 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.964
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.951
ald
Aldehyde dehydrogenase family protein, putative.
  
 0.933
ald-2
Aldehyde dehydrogenase family protein, putative; Belongs to the aldehyde dehydrogenase family.
  
 0.933
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 0.933
RD1_0025
Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.932
bktB
Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.932
phbA
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.932
fadA
Fatty acid oxidation complex beta subunit; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.932
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.925
Your Current Organism:
Roseobacter denitrificans
NCBI taxonomy Id: 375451
Other names: Erythrobacter sp. OCh114, R. denitrificans OCh 114, Roseobacter denitrificans ATCC 33942, Roseobacter denitrificans DSM 7001, Roseobacter denitrificans OCh 114, Roseobacter denitrificans str. OCh 114, Roseobacter denitrificans strain OCh 114, Roseobacter sp. OCh114
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