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lipA lipA lipB lipB KRH_12500 KRH_12500 KRH_14010 KRH_14010 gcvH gcvH nadA nadA sucA sucA KRH_14420 KRH_14420 KRH_14470 KRH_14470 gcvP gcvP folE folE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (335 aa)    
Predicted Functional Partners:
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.999
KRH_12500
Putative lipoate-protein ligase.
  
 
 0.936
KRH_14010
Hypothetical protein.
  
 
 0.920
gcvH
Glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.892
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
      
 0.610
sucA
2-oxoglutarate dehydrogenase E1 component; Protein synonym:alpha-ketoglutarate dehydrogenase.
 
  
 0.571
KRH_14420
Dihydrolipoamide acyltransferase.
 
  
 0.569
KRH_14470
Hypothetical membrane protein.
       0.567
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.562
folE
GTP cyclohydrolase I.
     
 0.559
Your Current Organism:
Kocuria rhizophila
NCBI taxonomy Id: 378753
Other names: K. rhizophila DC2201, Kocuria rhizophila ATCC 9341, Kocuria rhizophila DC2201, Kocuria rhizophila DSM 348, Kocuria rhizophila NBRC 103217, Kocuria rhizophila str. DC2201, Kocuria rhizophila strain DC2201, Micrococcus luteus ATCC 9341
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